Thuốc điều trị Hạ Natri máu

q4–6h

lên 120–125 mEq/L, nhưng không quá

12 mEq/L trong 24h đầu

mEq Na+/L)

ý)

mEq Na+/L)

chú ý)

nặng hoặc co giật. nên dùng thận trọng

bù nhanh có thể gây ngộ độc CNS

(hủy myelin cầu não) or quá tải dịch

lượn xa

of inappropriate antidiuretic hormone release

• Important to exclude “spurious” hyponatremia caused by hyperglycemia. This occurs because

the osmotically active solute, glucose, causes a shift of water from the intracellular compartment

to the extracellular compartment and dilutes extracellular sodium. For every 62 mg/dl

rise in glucose, there is a 1 mEq/L fall in sodium.

• The rate of correction of hyponatremia should be proportional to its rate of occurrence.

Acute correction of hyponatremia should not exceed a 20 mEq/L rise in concentration of

serum sodium in the first 48 hours of therapy.

• Osmolality (mOsm/kg) = 2(Na+ + K+) + (BUN/2.8) + (glucose/18).