xử trí phản vệ
Situation | Intervention | Comments |
Systemic anaphylaxis | Epinephrine 1:1,000, 0.3 cc SC, repeat at 5-10 min intervals Diphenhydramine 25-100 mg IV | Repeat doses of diphenhydramine may be required for |
Special Problems | H2-blocker^ Hydrocortisone 100-250 mg IV q6h | symptom relief |
Upper airway | Nebulized racemic epinephrine, 0.3 ml | Administer oxygen; |
obstruction | diluted in 3 ml 0.9% NaCl | consider tracheal intubation and mechanical ventilation |
Bronchospasm | Epinephrine 1:1,000, 0.3-0.5 ml SC, may repeat at 5-10 min intervals, or Albuterol, 1-2 puffs metered dose inhaler or 2.5-5 mg nebulized in 2-3 ml 0.9% NaCl, or Aminophylline, 6 mg/kg IV initially (see Table 4.4) | With severe bronchospasm or hypotension, consider epinephrine, 1:10,000, 0.5-1.0 ml IV (rather than SC) |
Shock | Volume resuscitation with 0.9% NaCl >500 ml rapidly, with or without vasopressors Dopamine 5-20 ^g/kg/min, titrated to blood pressure, or Norepinephrine, 2 ^g/min, titrated to blood pressure Patients on ^-blockers who are hypotensive may also be treated with glucagon, 1 mg IV | |
IV, intravenous; SC, subcutaneous ^Ranitidine: 50 mg IV Famotidine: 20 mg IV Cimetidine: 300 mg IV |